Five Things You May Not Know About the Brain/System "Don't Miss"
Eating food fried in oil not only adds calories to the daily menu but can also cause several health risks. Researchers have now found that frequent reuse of frying oil, a common practice in many homes and restaurants, may increase the risk of neurodegeneration and brain damage.
According to the results of a study conducted on rats and presented at Discover BMB 2024, the annual meeting of the American Society for Biochemistry and Molecular Biology, diets containing heated cooking oils led to significantly increased levels of neurodegeneration compared to a standard diet.
"Deep-frying at high temperatures has been linked to a number of metabolic disorders, but there have been no long-term investigations into the effect of deep-fried oil consumption and its harmful effects on health. To the best of our knowledge, we are the first to report long-term damage. Deep-fried oil supplements increase neurodegeneration in first-generation offspring." , said Prof. Katharsen Shanmugam of the Central University of Tamil Nadu, India, who led the study.
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The rats that participated in the study were divided into five groups. Each group received standard food alone or standard food plus 0.1 ml per day of unheated sesame oil, unheated sunflower oil, reheated sesame oil or heated sunflower oil for 30 days. The heated oils were used to simulate the effects of frying oil used repeated.
The rats that consumed reheated sesame or sunflower oil suffered from oxidative stress and increased inflammation in the liver. In addition, they also had significant damage to the colon and associated changes in endotoxins—toxins released from certain bacteria.
The researchers noted higher levels of neurodegeneration in the rats that consumed the heated oil and their offspring compared to the rats. in a normal diet. This is attributed to the disruption of the liver-intestine-brain axis associated with the reheated oil.
"As a result, the metabolism of fats in the liver has changed significantly, and the transport of the important omega-3 fatty acid DHA in the brain has decreased. This, in turn, resulted in neurodegeneration, which was seen in the histology of the brains of the rats that consumed the reheated oil, as well as their offspring," the researchers wrote.
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